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Mitochondria-related mechanisms

Reviews

New roles for mitochondria in cell death in thereperfused myocardium
Sang-Bing Ong, Åsa B. Gustafsson

The mPTP and its regulatory proteins: final common targets of signalling pathways for protection against necrosis
Tetsuji Miura, Masaya Tanno

Metabolic fingerprint of ischaemic cardioprotection: importance of the malate–aspartate shuttle
Torsten Toftegaard Nielsen, Nicolaj Brejnholt Støttrup, Bo Løfgren, Hans Erik Bøtker

What can we learn about cardioprotection from the cardiac mitochondrial proteome?
Marjan Gucek, Elizabeth Murphy

The SR–mitochondria interaction: a new player in cardiac pathophysiology
Marisol Ruiz-Meana, Celia Fernandez-Sanz, David Garcia-Dorado

Mitochondrial kinase signalling pathways in myocardial protection from ischaemia/reperfusion-induced necrosis
Tetsuji Miura, Masaya Tanno, Tatsuya Sato

Regulation and pharmacology of the mitochondrial permeability transition pore
Dmitry B. Zorov, Magdalena Juhaszova, Yael Yaniv, H. Bradley Nuss, Su Wang, Steven J. Sollott

Original articles

NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter
Vu Thi Thu, Hyoung-Kyu Kim, Le Thanh Long,
Sung-Ryul Lee, Tran My Hanh, Tae Hee Ko,
Hye-Jin Heo, Nari Kim, Soon Ha Kim, Kyung Soo Ko, Byoung Doo Rhee, Jin Han

Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation
Sean M. Davidson, Derek M. Yellon, Michael P. Murphy, Michael R. Duchen

Type 10 adenylyl cyclase mediates mitochondrial Bax translocation and apoptosis of adult rat cardiomyocytes under simulated ischaemia/reperfusion
Avinash Appukuttan, Sascha A. Kasseckert, Mustafa Micoogullari, Jan-Paul Flacke, Sanjeev Kumar, Alexandra Woste, Yaser Abdallah, Lutz Pott, H. Peter Reusch, Yury Ladilov

Mitochondria-specific transgenic overexpression of connexin-43 simulates preconditioning-induced cytoprotection of stem cells
Gang Lu, Husnain Kh Haider, Aleksey Porollo, Muhammad Ashraf

Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury
Grant R. Budas, Eric N. Churchill, Marie-Hélène Disatnik, Lihan Sun, Daria Mochly-Rosen

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning
Derek J. Hausenloy, Shiang Y. Lim, Sang-Ging Ong, Sean M. Davidson, Derek M. Yellon

Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction
Renaud Tissier, Nicolas Couvreur, Bijan Ghaleh, Patrick Bruneval, Fanny Lidouren, Didier Morin, Roland Zini, Alain Bize, Mourad Chenoune, Marie-France Belair, Chantal Mandet, Martine Douheret, Jean-Luc Dubois-Rande, James C. Parker, Michael V. Cohen, Jam

The targeting of cyclophilin D by RNAi as a novel cardioprotective therapy: evidence from two-photon imaging
Masashi Kato, Masaharu Akao, Madoka Matsumoto-Ida, Takeru Makiyama, Moritake Iguchi, Toshihiro Takeda, Shigeomi Shimizu, Toru Kita

Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection
Sergiy M. Nadtochiy, Paul R.S. Baker, Bruce A. Freeman, Paul S. Brookes