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Effects of oxygen inhalation on intramyocardial oxygen tension

Arthur J. Moss, James Johnson
DOI: http://dx.doi.org/10.1093/cvr/4.4.436 436-440 First published online: 1 October 1970

Authors' synopsis

Quantitative intramyocardial oxygen tension measurements were made in seven anaesthetized dogs using a polarographic technique. One hundred per cent oxygen inhalation produced only a modest 7 mm Hg increase in intramyocardial oxygen tension (16 to 23 mm Hg pO2) despite a five-fold increase in arterial blood oxygen tension. These experimental findings are in agreement with basic theoretical considerations and raise certain fundamental questions about the value of oxygen therapy in acute myocardial infarction.