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Cardiovascular Research Advance Access originally published online on June 9, 2009
Cardiovascular Research 2009 83(2):163-164; doi:10.1093/cvr/cvp186
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org.

Cardiac protection takes off

Hans Michael Piper1,* and David Garcia-Dorado2

1 Institute of Physiology, Justus Liebig University, Aulweg 129, 35392 Giessen, Germany
2 Hospital Universitari Vall d'Hebron, Area del Cor, 08035 Barcelona, Spain

* Corresponding author. Tel: +49 641 9947 241; fax: +49 641 9947 239; E-mail address: cvr@physiologie.med.uni-giessen.de

The first 10% of the full text of this article appears below.

Protecting the heart from ischaemia- and reperfusion-induced injury represents the greatest challenge of cardiology, since myocardial infarction is the major cause of mortality in industrialized countries. Research on cardiac protection has a long history in the discovery of new principles of protection, replete with triumphs but also broken dreams with respect to their clinical application. Treatment of acute myocardial infarction nowadays commences with a rapid opening of the occluded coronary vessel by percutaneous coronary intervention (PCI). When recanalization is achieved, ischaemia is followed by reperfusion. Even though reperfusion restores blood flow, . . . [Full Text of this Article]


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