Cardiovascular Research Advance Access originally published online on February 19, 2008
Cardiovascular Research 2008 78(1):198; doi:10.1093/cvr/cvn047
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org
Cyanide and uncoupling protein function: reply
Division of Pharmacology
University of Antwerp
Universiteitsplein 1
B-2610 Wilrijk
Belgium
Division of Pharmacology
University of Antwerp
Universiteitsplein 1
B-2610 Wilrijk
Belgium
Division of Pharmacology
University of Antwerp
Universiteitsplein 1
B-2610 Wilrijk
Belgium
Tel: +32 3 820 2737
Fax: +32 3 820 2567
E-mail address: guido.demeyer@ua.ac.be
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We would like to thank Dr Eduardo Rial for the interest in our study and acknowledge his critical comment that sodium cyanide is not an appropriate compound to mimic the thermogenic properties of uncoupling protein 2 (UCP2). UCP2 uncouples adenosine triphosphate (ATP) production from mitochondrial respiration and thereby converts the loss