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Cardiovascular Research 2007 73(1):247-248; doi:10.1016/j.cardiores.2006.10.023
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Copyright © 2006, European Society of Cardiology

Does the adenosine A2A receptor stimulate the ryanodine receptor?

L. Venetucci, S.C. O'Neill and D.A. Eisner*

Unit of Cardiac Physiology, University of Manchester, 3.18 Core Technology Facility, 46 Grafton St, Manchester M13 9NT, UK

* Corresponding author. Email address: eisner@man.ac.uk

Received 13 October 2006; accepted 27 October 2006

The first 10% of the full text of this article appears below.

A recent paper in Cardiovascular Research from Hove-Madsen and colleagues [1] has investigated the role of the adenosine A2A receptor in human atrial myocytes. Elegant confocal images show that this receptor is localized at the level of the Z line in the myocyte. Their paper then proceeds to address an important physiological question; the role of this receptor. No effect was found on the amplitude or voltage-dependence of the L-type Ca . . . [Full Text of this Article]


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L. Hove-Madsen, C. Prat-Vidal, A. Llach, F. Ciruela, V. Casado, C. Lluis, A. Bayes-Genis, J. Cinca, and R. Franco
Reply: Does the adenosine A2A receptor stimulate the ryanodine receptor?
Cardiovasc Res, January 1, 2007; 73(1): 249 - 250.
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