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Cardiovascular Research 2004 63(3):443-449; doi:10.1016/j.cardiores.2004.05.004
© 2004 by European Society of Cardiology
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Copyright © 2004, European Society of Cardiology

Interactions between the sympathetic nervous system and the cardiac natriuretic peptide system

A Luchner*,a and H Schunkertb

aKlinik und Poliklinik für Innere Medizin II, Klinikum der Universität Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg 93042, Germany
bMedizinische Klinik II, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck 23538, Germany

* Corresponding author. Tel.: +49-941-944-7211; fax: +49-941-944-7213. Email address: andreas.luchner{at}klinik.uni-regensburg.de

The sympathetic nervous system (SNS) and the cardiac natriuretic peptide system (NPS) are fundamentally important neurohumoral systems for cardiovascular regulation. Their mutual interactions have been subject to numerous experimental and human studies. In the current manuscript, results from in vivo and in vitro studies will be reviewed with a focus on sympathetic outflow on the control of natriuretic peptide release.

KEYWORDS Sympathetic nervous system; Alpha receptor; Beta-receptor; Heart failure; ANP; Natriuretic peptides; Interactions; Cross-talk

Time for primary review 23 days


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