© 2004 by European Society of Cardiology
Copyright © 2004, European Society of Cardiology
Experimental and clinical parameters of cardiac reverse remodeling after LVAD support: a call for uniformity
aInstitute of Pathology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
bDepartment of Pathophysiology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
* Corresponding author. Institut für Arterioskleroseforschung an der Universität Münster Domagkstr. 3 48149 Münster, Germany. Tel.: +49-251-835-8625; fax: +49-251-835-6088. levkau@uni-muenster.de
Received 15 October 2003; accepted 23 October 2003
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We are grateful for the comments of Razeghi et al. elicited by our recent report [1] on the important issue of comparability of experimental data raised from myocardial tissue samples among different studies on cardiac reverse remodeling under LVAD support. We completely agree that there are a number of non-standardized parameters among the different studies published thus far that make the direct comparison of experimental data difficult. These include patient characteristics and the underlying cause of heart failure as well as the make, duration and degree of LVAD support. In addition, we wish to emphasize another critical issue missing in most studies published thus far in