© 2002 by European Society of Cardiology
Copyright © 2002, European Society of Cardiology
Angiogenesis? the answer is NO·
Terrence Donnelly Vascular Biology Laboratory, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada
* Corresponding author. Tel.: +1-416-864-5724; fax: +1-416-864-5419 stewartd@smh.toronto.on.ca
Received 16 September 2002; accepted 18 September 2002
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We thank Drs Dulak and Jozkowicz for their interest in our paper [1]. They raise the question of whether induction of VEGF expression by NO in cultured smooth muscle cells (SMCs) may have contributed to the angiogenic effects of eNOS in our co-culture model. Although, we agree that this