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Cardiovascular Research 2002 54(1):193-194; doi:10.1016/S0008-6363(02)00285-7
© 2002 by European Society of Cardiology
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Copyright © 2002, European Society of Cardiology

Von Willebrand factor and assessment of endothelial function

Jan Malik*, Dan Wichterle, Vojtech Melenovsky and Jan Simek

Third Department of Medicine, Charles University, First School of Medicine and General University Hospital, U Nemocnice 1, Prague 2, 128 08, Czech Republic

* Corresponding author. Tel./fax: +42-2-2492-3852 jmali@lf1.cuni.cz

Received 6 February 2002; accepted 6 February 2002

The first 10% of the full text of this article appears below.

We thank Prof. Lip et al. for their comments, which focused on the reproducibility of methods used for the assessment of endothelial function. It has been shown in our paper that flow mediated dilatation (FMD) has considerably worse reproducibility than peak blood flow (PBF). This observation is in contradiction to the widespread opinion that FMD is generally a reproducible technique, suitable even for an individual risk assessment [1]. Poor reproducibility of . . . [Full Text of this Article]


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