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Cardiovascular Research 2001 51(1):7-8; doi:10.1016/S0008-6363(01)00334-0
© 2001 by European Society of Cardiology
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Copyright © 2000, European Society of Cardiology

Perinatal vascular development

Rosemary D Higgins* and Martin Keszler

Department of Pediatrics, Division of Neonatology, Georgetown University Children's Medical Center, 3800 Reservoir Road, NW, Room M3400, Washington, DC 20007, USA

higginsr1@georgetown.edu

* Corresponding author. Tel.: +1-202-687-8569; fax: +1-202-784-4747

The first 10% of the full text of this article appears below.

See article by Boels et al. [3] (pages 140–150) in this issue.

During transition to the extrauterine environment, the newborn infant must accomplish complex cardiorespiratory adjustments. Dramatic changes in pulmonary and systemic vascular resistance must occur within minutes, followed by more gradual changes over the succeeding days. A host of mediators of vascular tone are involved in these processes and these have been the focus of extensive study. Differential responses from different . . . [Full Text of this Article]


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