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Cardiovascular Research 1999 42(1):45-47; doi:10.1016/S0008-6363(99)00003-6
© 1999 by European Society of Cardiology
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Copyright © 1999, European Society of Cardiology

Concerning thromboembolism associated with left ventricular assist devices

David R. Gross*

3516 VMBS Building, 2001 S. Lincoln Avenue, Urbana, IL 61802, USA

* Tel.: +1-217-333-2506; fax +1-217-244-1560. Dr. Gross was formerly Professor and Director of the Cardiovascular Surgery Research Laboratories, Division of Cardiovascular and Thoracic Surgery, College of Medicine, University of Kentucky. He is currently Professor and Head, Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois, Urbana-Champaign.

Received 15 December 1998; accepted 15 December 1998

The first 10% of the full text of this article appears below.


   1 Introduction
 
Cardiac surgeons are obligated to find solutions for patients with end-stage cardiac failure. Cardiac transplantation has provided the most successful option thus far but demand far exceeds the supply of donor hearts and demand is projected to increase while supply will level off, or perhaps decline [1]. Because of this shortfall in donor hearts there has been continued effort and emphasis on development of alternatives to cardiac transplantation [2]. Recently it was estimated that by the year 2010 between 35 000 and 70 000 patients in the USA alone would be candidates for permanent cardiac replacement or support [3].


   2 Early experience
 
Early versions of blood pumping devices, most containing silicone rubber blood sacs, experienced major problems with thrombosis. [4] Dacron-flocked surfaces were promulgated as a solution, the . . . [Full Text of this Article]


   3 Thromboembolism
 

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