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Cardiovascular Research 1967 1(4):327-334; doi:10.1093/cvr/1.4.327
© 1967 by European Society of Cardiology
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Copyright © 1967, European Society of Cardiology

Reduction in the Vasoconstriction Produced by Sympathetic Adrenergic Nerves during Reactive Hyperaemia*

B. L. Ardill{dagger}, V. M. Bhatnagar{ddagger} and P. H. Fentem

From the Department of Physiology, St. Mary's Hospital Medical School, London

{dagger} Beit Memorial Research Fellow.

{ddagger} Colombo Plan Fellow. Present address: The Department of Physiology, The Medical College, Kanpur, 2, U.P. India.

Authors' Synopsis: The intense reflex sympathetic vasoconstriction of forearm vessels induced by exposure of the parts of the body distal to the xiphisternum to pressures 60 mm Hg below atmospheric is able to reduce the reactive hyperaemia that follows a period of occlusion of the forearm circulation. Following occlusion for periods of from 15 sec to 8 min, the duration of the reactive hyperaemia, the peak flow, and the excess blood flow were reduced.

* This work was supported by research grants from the British Heart Foundation to Professor A. D. M. Greenfield and the Sir Halley Stewart Trust to P.H.F.


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