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Cardiovascular Research 1967 1(3):229-232; doi:10.1093/cvr/1.3.229
© 1967 by European Society of Cardiology
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Copyright © 1967, European Society of Cardiology

Validity of the 133Xenon Method for Determination of Muscle Blood Flow in Man as Evaluated by Simultaneous Venous Occlusion Plethysmography during Intravenous Infusions of Adrenaline

H. Barcroft, M. Briggs*, T. M. D. Gimlette{dagger} and A. Nasrallah{ddagger}

From St. Thomas's Hospital Medical School, London

* Department of Neurological Surgery, Radcliffe Infirmary, Oxford.

{dagger} Department of Nuclear Medicine, Liverpool Clinic, 1 Myrtle Street, Liverpool 1.

{ddagger} Supported by a grant from the Calouste Gulbenkian Foundation.

Authors' Synopsis: Intravenous infusions of adrenaline (10 µg/min) were accompanied by a transient increase in blood flow both in the forearm and calf (plethysmograph) and in the brachioradialis and gastrocnemius muscles (133Xenon clearance). The results confirm the view that the 133Xenon method is useful for determining changes in skeletal muscle blood flow.


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