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Cardiovascular Research 1967 1(2):150-158; doi:10.1093/cvr/1.2.150
© 1967 by European Society of Cardiology
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Copyright © 1967, European Society of Cardiology

Second Degree Atrioventricular Block*

Yoshio Watanabe and Leonard S. Dreifus

From the Cardiovascular Section, Department of Medicine, Hahnemann Medical College, Philadelphia, Pennsylvania, U.S.A.

Authors' Synopsis: Mechanisms of clinically known varieties of second degree A-V block were studied in isolated rabbit hearts, utilizing ultramicroelectrode techniques. Progressive A-V conduction delay in Wenckebach phenomenon was due mainly to depressed conduction within the A-V node, while Mobitz type 2 block was due to either block in or below His bundle or concealed re-excitation in the A-V junction. Two levels of block were demonstrated both in forward and retrograde A-V transmission.

* This study was supported by Grant (HE 07136) from the Public Health Service.


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