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Corrigendum for Poulos et al., Cardiovasc Res 32 (5) 909-919.
Cardiovascular Research 2002 55(2):238; doi:10.1016/S0008-6363(02)00495-9
© 2002 by European Society of Cardiology
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Copyright © 2002, European Society of Cardiology

Congestive heart failure: increased cardiac and extracardiac atrial natriuretic peptide gene expression

John E Poulos, William R Gower, Jr., Thompson Sullebarger, Hector L Fontanet and David L Vesely*

J.A. Haley Veterans Hospital – 151, University of South Florida Cardiac Hormone Center, 13000 Bruce B. Downs Blvd., Tampa, FL 33612, USA

* Corresponding author. Tel.: +1-813-972-7624; fax: +1-813-972-7623 vesely.david_l{at}tampa.va.gov

Figs. 7 and 8Go of the article by Poulos et al. in Cardiovascular Research 1996;32:909–919 were inadvertently the plotted values for high performance-gel permeation chromatography (HP-GPC) of healthy humans rather than the plotted values of rat congestive heart failure plasma as shown in the overleaf.


Figure 7
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  		Fig. 7 High-performance gel-permeation chromatography followed by vessel dilator (i.e., proANF 31-67) radioimmunoassay of each 0.3 ml fraction obtained from plasma of rats with congestive heart failure revealed that vessel dilator exists in plasma as a distinct peptide. The elution of vessel dilator from plasma was identical with the pure synthetic form of vessel dilator (arrow). Vt=total volume of column; Vo=void volume of column.

 

Figure 8
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  		Fig. 8 Atrial natriuretic peptide (ANP) exists as a separate entity in plasma of rats with congestive heart failure as determined by high-performance gel-permeation chromatography (HP-GPC). One distinct peak in plasma consisting of 0.3 ml fractions 74–79 with the peak in fraction 77 was found with HP-GPC evaluation followed by atrial natriuretic peptide radioinimunoassay. This peak in plasma was identical to where the pure synthetic sequence of ANP eluted (arrow). Vt,=total volume of column; Vo=void volume of column.

 
The HP-GPC data for healthy humans has been published in Circulation 1994;90:129–140 with a typical HP-GPC plot of healthy human plasma and urine also in Peptides 1994;15:861–867.

The authors deeply regret sending the wrong figures and apologize for any confusion caused by this oversight.


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Congestive heart failure: increased cardiac and extracardiac atrial natriuretic peptide gene expression
John E. Poulos, William R. Gower, Jr., J.Thompson Sullebarger, Hector L. Fontanet, and David L. Vesely
Cardiovasc Res 1996 32: 909-919. [Abstract] [PDF]




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