Skip Navigation


Cardiovascular Research Advance Access originally published online on January 15, 2009
Cardiovascular Research 2009 81(4):627-628; doi:10.1093/cvr/cvp018
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
81/4/627    most recent
cvp018v2
cvp018v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Agrotis, A.
Right arrow Articles by Koulis, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Agrotis, A.
Right arrow Articles by Koulis, C.
Related Collections
Right arrowRelated Article
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

STIM1: a new therapeutic target in occlusive vascular disease?

Alex Agrotis* and Christine Koulis

Vascular Biology and Atherosclerosis Laboratory, Baker IDI Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia

* Corresponding author. Tel: +61 3 8532 1189; fax: +61 3 8532 1100. E-mail address: alex.agrotis@bakeridi.edu.au

This editorial refers to ‘An essential role for stromal interaction molecule 1 in neointima formation following arterial injury’ by Rui-Wei Guo et al.,8 pp. 660–668, this issue.

The first 10% of the full text of this article appears below.

Improvements in interventional cardiology arising from stent development have significantly increased the efficacy of angioplasty as a primary treatment for atherosclerotic artery disease. Nevertheless, this procedure is still prone to failure in some patients due to the occurrence of neointimal hyperplasia that contributes to restenosis, lumen loss, and reduction in blood flow. In addition, late-stent thrombotic complications may also arise in some instances in which anti-proliferative drug-eluting stents are used, due to compromised reendothelialization subsequent to the angioplasty procedure. The development of neointimal hyperplasia is a complex phenomenon, with multiple mechanisms and molecules being involved. Angioplastic denudation of the endothelial barrier overlying the smooth muscle cell . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related Article

An essential role for stromal interaction molecule 1 in neointima formation following arterial injury
Rui-Wei Guo, Hong Wang, Pan Gao, Mao-Quan Li, Chun-Yu Zeng, Yang Yu, Jian-Fei Chen, Ming-Bao Song, Yan-Kun Shi, and Lan Huang
Cardiovasc Res 2009 81: 660-668. [Abstract] [Full Text] [PDF]