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Cardiovascular Research Advance Access originally published online on December 4, 2007
Cardiovascular Research 2008 77(3):445-447; doi:10.1093/cvr/cvm088
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

Circulating smooth muscle progenitor cells: novel players in plaque stability

Kimio Satoh and Bradford C. Berk*

Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Box 706, 601 Elmwood Avenue, Rochester, NY 14642, USA

* Corresponding author. Tel: +1 585 275 3407; fax: +1 585 273 1059. E-mail address: bradford_berk@urmc.rochester.edu

This editorial refers to ‘Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition’ by Zoll et al., pp. 471–480.

The first 10% of the full text of this article appears below.

Our understanding of the role of stem cells in the pathogenesis of vascular disease has been rapidly evolving. It is generally accepted that bone marrow (BM)-derived endothelial progenitor cells (EPCs) participate in arterial repair and angiogenesis after injury by homing to the injured vessel and differentiating into endothelial cells.1 BM-derived cells with smooth muscle cell (SMC)-like phenotype also participate in the pathogenesis of vascular disease.2 Recently, Simper et al.3 reported the existence of smooth muscle progenitor cells (SPCs) in human blood. Hashimoto et al. . . [Full Text of this Article]


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Related articles in Cardiovasc Res:

Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition
Joffrey Zoll, Vincent Fontaine, Pierre Gourdy, Veronique Barateau, Jose Vilar, Aurelie Leroyer, Izolina Lopes-Kam, Ziad Mallat, Jean-Francois Arnal, Patrick Henry, Gerard Tobelem, and Alain Tedgui
Cardiovasc Res 2008 77: 471-480. [Abstract] [Full Text]  

Related Article

Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition
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Cardiovasc Res 2008 77: 471-480. [Abstract] [Full Text] [PDF]