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Cardiovascular Research 2007 76(1):1-2; doi:10.1016/j.cardiores.2007.07.010
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Copyright © 2007, European Society of Cardiology

Something is rotten in the state of angiogenesis — H2S as gaseous stimulator of angiogenesis

Imo E. Hoefer*

Experimental Cardiology, UMC Utrecht, G02.523, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands

*Tel.: +31 30 250 7155; fax: +31 30 252 2693. i.hoefer@umcutrecht.nl

Received 4 July 2007; accepted 18 July 2007

The first 10% of the full text of this article appears below.

See article by Cai et al. [7] (pages 29–40) in this issue.

The research on a new class of signaling molecules, later named gaseous transmitters or gasotransmitters, started in 1986 with the discovery that the so-called endothelium-derived relaxing factor (EDRF) is identical to nitric oxide [1]. This finding was later awarded with the Nobel Prize and NO was named "molecule of the year" in 1992. Since then, countless studies have focused on the role of NO in various processes, among which its cardiovascular effects still remain most prominent. A few years later, NO was accompanied . . . [Full Text of this Article]


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