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Cardiovascular Research 2007 75(4):634-635; doi:10.1016/j.cardiores.2007.06.031
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Copyright © 2007, European Society of Cardiology

Osteopontin, a missing link in PDGF-induced smooth muscle cell migration

Kristina Boström*

Division of Cardiology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095-1679, United States
Molecular Biology Institute, UCLA, Los Angeles, CA 90095-1570, United States

* Division of Cardiology, David Geffen School of Medicine at UCLA, Box 951679, Los Angeles, CA 90095-1679, United States. Tel.: +1 310 794 4417; fax: +1 310 2068553. kbostrom@mednet.ucla.edu

Received 25 June 2007; accepted 29 June 2007

The first 10% of the full text of this article appears below.

See article by Jalvy et al. [8] (pages 738–747) in this issue.

Cell migration might be considered one of the most basic requirements in vascular development and one of the most basic problems in vascular disease. Recruitment of precursors to vascular smooth muscle cells (SMC) is essential for the formation of vascular media in embryonic development [1], but it also fuels the growth of atherosclerotic plaques and neointimal hyperplasia after angioplasty [2,3]. . . . [Full Text of this Article]


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