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Cardiovascular Research 2006 69(1):9-12; doi:10.1016/j.cardiores.2005.10.005
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Copyright © 2005, European Society of Cardiology

Large meals and large arteries: Is resistin the link?

Joerg Herrmann*

Department of Internal Medicine, Mayo Clinic Rochester, 200 First Street S.W. Rochester, MN, 55905, USA

* Tel.: +1 507 255 5890; fax: +1 507 255 1824. Email address: herrmann.joerg@mayo.edu

Received 17 October 2005; accepted 21 October 2005

The first 150 words of the full text of this article appear below.

See article by Jung et al. [11] (pages 76–85) in this issue.

"To lengthen thy Life, lessen thy Meals."

Benjamin Franklin, Poor Richard's Almanack, 1733

The burden of chronic diseases is on the rise on all continents, and the predictions for its detrimental effects on the individual and society resemble the warnings of a hurricane approaching land [1]. Most of the storm settles on complications of cardiovascular disease, the risk of which is increased by a factor of two to three even by the clustering of "prestages" of traditional cardiovascular factors, referred to as the "metabolic syndrome" and related to insulin resistance ever since Reaven's seminal work in 1987 [2]. Five different major sets of criteria are currently in place for the diagnosis of the metabolic syndrome, with the entire concept being very critically appraised by representatives of American and European diabetes societies, yet again endorsed by the . . . [Full Text of this Article]


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