Copyright © 2005, European Society of Cardiology
Dying for attention: Microparticles and angiogenesis
Cardiovascular Research Center INSERM Lariboisière, 75475 Paris cedex 10, France
* Corresponding author. Tel.: +33 1 4463 1864; fax: +33 1 4281 3128. Email address: chantal.boulanger@larib.inserm.fr
Received 28 April 2005; accepted 2 May 2005
| The first 10% of the full text of this article appears below. |
See article by Brill et al. [18] (pages 30–38) in this issue.
Microparticles, which were initially described as cell dust, have revealed over the past few years several exciting and unexpected properties. Microparticles are submicron vesicles shed from plasma membranes following cell activation or apoptosis, whose protein and lipid profile may be considered as a snapshot of the phenotype of the cell they stem from. The molecular mechanisms of microparticle formation and shedding are not yet fully understood, but seem to involve the changes in the
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