Copyright © 2005, European Society of Cardiology
Human umbilical cord blood cells and myocardial infarction: Novel ways to treat an old problem
Klinik für Innere Medizin III, Kardiologie, Angiologie, Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Strasse, D-66421 Homburg/Saar, Germany
* Corresponding author. Tel.: +49 6841 162 3372; fax: +49 6841 162 3369. Email address: efriedrich@med-in.uni-sb.de boehm@med-in.uni-sb.de
Received 21 January 2005; accepted 21 January 2005
| The first 10% of the full text of this article appears below. |
See article by Ma et al. [4] (pages 45–54) in this issue.
Myocardial infarction and its consequences such as congestive heart failure continue to be a major cause of death in Western societies despite therapeutic advances made in recent years. A growing body of evidence indicates that cell-based strategies might have promising therapeutic potentials for cardiac revascularization and the restoration of cardiac function. In that respect, several recent experimental studies have demonstrated varying degrees of cardiac regeneration using different stem cell populations such as embryonic stem cells, skeletal myoblasts, hematopoietic stem cells, endothelial progenitor cells, and mesenchymal stem cells [1,2]. Similarly, our group has detected cardiac regeneration by cells of non-cardiac origin in biopsies
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