© 2003 by European Society of Cardiology
Copyright © 2003, European Society of Cardiology
Do we understand why regression of left ventricular hypertrophy is beneficial?
Tel Aviv University, Israel
Received 13 October 2003; revised 13 October 2003; accepted 13 October 2003
| The first 10% of the full text of this article appears below. |
See article by Botchway et al. [12] (pages 510–517) in this issue.
Hypertrophy is the mechanism by which muscle, any muscle, copes with persistent and repetitive overloads. Any increase in cardiac chamber radius (r) and/or pressure (p) will result in a proportional increase in total wall tension (T) according to the ideal Laplace formula, T = pr. The true load on the individual myocardial fibers can be appreciated by dividing the tension by the width of the chamber wall (h): Ts=(pr)/h.