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Cardiovascular Research 2001 50(2):173-176; doi:10.1016/S0008-6363(01)00270-X
© 2001 by European Society of Cardiology
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Copyright © 2001, European Society of Cardiology

Spotlight on sudden cardiac death

Peter M Spoonera,*, Silvia G Priorib and Robert J Myerburgc

aArrhythmia Research Group, DHVD, National Heart, Lung & Blood Institute, 2 Rockledge Ctr., MSC-7940, 6701 Rockledge Dr., Bethesda, MD 20892, USA
bMolecular Cardiology, Fondazione Salvatore Maugeri, Via Ferrata 8, 27100 Pavia, Italy
cDivision of Cardiology, University of Miami School of Medicine, Miami, FL, USA

* Corresponding author. Tel.: +1-301-435-0507; fax: +1-301-480-1454

Received 26 February 2001; accepted 27 February 2001

The first 150 words of the full text of this article appear below.

Sudden cardiac death (SCD) is a very common mechanism for cardiac mortality in all developed nations, yet means to identify individuals at increased risk for this condition and effective strategies for its prevention remain elusive. For many years the focus of SCD research has concentrated on averting those conditions that are its primary antecedents, such as athero-thrombotic coronary artery disease, hypertension and heart failure. Recently however, major advances have occurred in understanding those more immediate cellular and molecular influences that contribute to the overall prevalence of SCD and the mechanisms responsible for its initiation in both apparently healthy individuals and those with established cardiac diseases. This "Spotlight" issue of the Journal has been designed to highlight many of these new discoveries and the remarkable progress and challenges that characterize this field today.

A number of factors have contributed to the difficulties that characterize the historically slow pace of progress in . . . [Full Text of this Article]


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