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Cardiovascular Research 2001 49(1):15-16; doi:10.1016/S0008-6363(00)00276-5
© 2001 by European Society of Cardiology
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Copyright © 2000, European Society of Cardiology

A role for endothelin receptor blockade in improving the endothelial function of coronary artery grafts?

Nico Hoogerwerf*

Academic Medical Center, Department of Anesthesiology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

* Corresponding author. Tel.: +31-20-566-3325; fax: +31-20-697-9441 n.hoogerwerf@amc.uva.nl

Received 26 October 2000; accepted 30 October 2000

The first 10% of the full text of this article appears below.

See article by Verma et al. [4] (pages 146–151) in this issue.

Since the experiments of Furchgott and Zawadzki [1] at the end-seventies, there is an increased number of research projects on the endothelium and the endothelial function in vascular regulation. The experimental data produced then has reached tremendous quantities. Now we know that the endothelium plays a role as an autocrine and paracrine producer of vascular active substances [2], either with a constricting or a dilating effect of blood vessels, . . . [Full Text of this Article]


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Endothelin receptor blockade and nitric oxide bioactivity: [Cardiovascular Research 2001;49:146-151]
Cardiovasc Res, October 1, 2001; 52(1): 161 - 163.
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