© 2000 by European Society of Cardiology
Copyright © 2000, European Society of Cardiology
Arrhythmogenic action of endothelin-1
Department of Cardiovascular Surgery, Semmelweis University Budapest, Városmajor u.68, H-1122 Hungary
* Corresponding author. Tel.: +36-1-355-4984; fax: +36-1-355-4684 merkbel@hermes.sote.hu
Received 3 August 2000; accepted 8 August 2000
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Dear Editor,
It was highly interesting to read the Letter to the Editor by Duru et al. [1] regarding the arrhythmogenic action of endothelin-1 (ET-1). ET-1 is supposed to act as a paracrine hormone released due to stretch or myocardial ischaemia in vivo. ET-1 prolonged action potential duration with early