© 2000 by European Society of Cardiology
Copyright © 2000, European Society of Cardiology
Quantification of electrical remodeling in human atrial fibrillation
Department of Cardiology, University Hospital Magdeburg, Magdeburg, Germany
* Tel.: +49-391-671-3203; fax: +49-391-671-3202 andreas.bollmann@medizin.uni-magdeburg.de
Received 18 May 2000; accepted 19 May 2000
| The first 10% of the full text of this article appears below. |
See article by Manios et al. [10] (pages 244–253) in this issue.
Mapping of the atrial electrical activation pattern during human Atrial Fibrillation (AF) has provided evidence supporting Moe's hypothesis that AF is based on the continuous propagation of multiple wavelets wandering throughout the atria in the majority of cases [1]. Since the average size of reentry pathways during AF is dependent on atrial wavelength (conduction velocityxrefractory period) it is not surprising that different complex atrial activation patterns with different numbers and dimensions of the reentry circuits were found. While long wavelengths are associated with larger and fewer wavefronts, short wavelengths result in a greater number of smaller circuits. A numerical index for quantification of spatial AF organization was proposed and applied to different AF patterns by Botteron and Smith [2]. These authors, by calculating