© 2000 by European Society of Cardiology
Copyright © 2000, European Society of Cardiology
Messenger RNA expression and immunological quantification of phospholamban and SR-Ca2+-ATPase in failing and nonfailing human hearts
Institüt für Pharmacologie und Toxikologie, Westfalische Wilhelms-Universität, Domagkstr 12, 48129 Münster, Germany
* Corresponding author. Tel.: +49-251-83-55510; fax: +49-251-83-55501
KEYWORDS Calcium (cellular); Genetic code; Heart failure; SR (function); Ventricular function
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In the past, there was good evidence that the β-adrenoceptor/adenylycyclase signaling pathway leads to a defective production of cAMP and hence to a reduced contractility in human end-stage heart failure [1,2]. But when we