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Cardiovascular Research 1999 42(3):600-606; doi:10.1016/S0008-6363(99)00020-6
© 1999 by European Society of Cardiology
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Copyright © 1999, European Society of Cardiology

Spotlight on microcirculation: an update

Isabella Tritto and Giuseppe Ambrosio*

Division of Cardiology, Department of Clinical and Experimental Medicine, University of Perugia, Via Eugubina 42, 06122 Perugia, Italy

cardiopg@unipg.it

* Corresponding author. Tel.: +39-75-585-5842; fax: +39-75-585-5840

Received 8 July 1998; accepted 15 January 1999

The first 150 words of the full text of this article appear below.


   1 Introduction
 
Over the past 3 decades there has been an increasing interest in the better understanding of the role of microcirculation under a variety of conditions. Therefore, in 1996 Cardiovascular Research devoted the whole October issue to microcirculation. Two years later the interest in this field is far from being reduced, as the number of articles published has remained high, with over 800 papers per year. The purpose of this article is to review several major studies which have appeared over the last 2 years in this field, which update the various key areas of research that were extensively reviewed in the 1996 issue.


   2 Microcirculation as the site of exchange of gases and metabolites
 
Oxygen delivery to tissue has long been considered to take place almost exclusively at the capillary level. However, it has progressively become appreciated that tissue oxygenation is the result of a complex process in which a substantial amount of oxygen is exchanged through arterioles, which in some . . . [Full Text of this Article]


   3 Biophysical mechanisms of flow regulation in microcirculation
 

   4 New mediators of microvascular regulation
 

   5 Microcirculation during inflammation
 

   6 Microvascular alterations in chronic diseases
 

   7 Microcirculation and angiogenesis
 

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