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Cardiovascular Research 2003 58(2):369-377; doi:10.1016/S0008-6363(02)00783-6
© 2003 by European Society of Cardiology
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Copyright © 2003, European Society of Cardiology

Stem cells and cardiac disorders: an appraisal

Michael J. Goldenthal and José Marín-García*

The Molecular Cardiology and Neuromuscular Institute, 75 Raritan Avenue, Highland Park, NJ 08904, USA

* Corresponding author. Tel.: +1-732-220-1719; fax: +1-732-220-2992. tmci{at}att.net

The use of stem cells has proved to be an important tool in investigating the events of early cardiac development, differentiation, and morphogenesis. In addition, stem cell transplantation in the treatment of certain cardiac disorders has shown early promise. We have attempted to present a balanced review of both basic studies and clinical–therapeutic potential of stem cells transplantation in the damaged heart.

KEYWORDS Stem cells; Myocytes; Mitochondria; Endothelial receptors; Ischemia


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