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Cardiovascular Research 2000 47(3):419-425; doi:10.1016/S0008-6363(00)00053-5
© 2000 by European Society of Cardiology
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Copyright © 2000, European Society of Cardiology

Diet and prevention of coronary heart disease: the potential role of phytochemicals

Francesco Visioli*, Luisa Borsani and Claudio Galli

University of Milan, Institute of Pharmacological Sciences, Via Balzaretti 9, 20133 Milan, Italy

* Corresponding author. Tel.: +39-2-2048-8217; fax: +39-2-2940-4961 francesco.visioli{at}unimi.it

Epidemiological studies, and some clinical trials, demonstrate that a proper diet reduces the rate of occurrence of cardiovascular disorders. Several in vitro studies suggest that some components of plant foods, most of which sharing a phenolic structure, are endowed with interesting ‘pharmacological activities’. This article reviews the evidence that links a high dietary intake of phytochemicals from various sources with a reduced incidence of coronary heart disease.

KEYWORDS Coronary disease; Epidemiology; Free radicals


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