Skip Navigation

Cardiovascular Research 2000 45(2):279-293; doi:10.1016/S0008-6363(99)00263-1
© 2000 by European Society of Cardiology
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by van der Vusse, G. J
Right arrow Articles by Glatz, J. F.C
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by van der Vusse, G. J
Right arrow Articles by Glatz, J. F.C
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Copyright © 2000, European Society of Cardiology

Cardiac fatty acid uptake and transport in health and disease

Ger J van der Vusse*, Marc van Bilsen and Jan F.C Glatz

Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands

* Corresponding author. Tel.: +31-43-388-1086; fax: +31-43-388-4166 vandervusse{at}fys.unimaas.nl

Fatty acids are important energy donors for the healthy heart. These substrates are supplied to the myocardium bound to albumin to overcome their low solubility in aqueous solutions such as blood plasma. Transport from the microvasular compartment to the mitochondria inside the cardiomyocytes is most likely a combination of passive and protein-mediated diffusion. Alterations in tissue content of fatty acid-transport proteins may contribute to myocardial diseases such as the diabetic heart, and cardiac hypertrophy and failure.

KEYWORDS Cardiomyopathy; Diabetes; Energy metabolism; Heart failure; Hypertrophy


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. S. Augustus, J. Buchanan, S. Addya, G. Rengo, R. G. Pestell, P. Fortina, W. J. Koch, A. Bensadoun, E. D. Abel, and M. P. Lisanti
Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts
Am J Physiol Heart Circ Physiol, August 1, 2008; 295(2): H657 - H666.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
R. W. Schwenk, J. J.F.P. Luiken, A. Bonen, and J. F.C. Glatz
Regulation of sarcolemmal glucose and fatty acid transporters in cardiac disease
Cardiovasc Res, July 15, 2008; 79(2): 249 - 258.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
J. R. Ussher and G. D. Lopaschuk
The malonyl CoA axis as a potential target for treating ischaemic heart disease
Cardiovasc Res, July 15, 2008; 79(2): 259 - 268.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
G. D. Lopaschuk and D. P. Kelly
Signalling in cardiac metabolism
Cardiovasc Res, July 15, 2008; 79(2): 205 - 207.
[Full Text] [PDF]

Home page
 Cardiovasc ResHome page
M. van Bilsen, P. J.H Smeets, A. J Gilde, and G. J van der Vusse
Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?
Cardiovasc Res, February 1, 2004; 61(2): 218 - 226.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.