© 1999 by European Society of Cardiology
Copyright © 1999, European Society of Cardiology
Electrical remodeling in ischemia and infarction
Department of Pharmacology, Columbia College of Physicians and Surgeons, 630 West 168th St., New York, NY 10032, USA
* Corresponding author. Tel.: +1-212-305-7907; fax: +1-212-305-0529
This is a review of the electrophysiologic changes occurring at different times following myocardial infarction, both in the infarcted region (substrate) and in areas remote from the infarct. Regulators of channel function which might contribute to re-modeling, including autocrine/paracrine factors involved in ion channel gene regulation, are discussed.
KEYWORDS Purkinje; Ventricular; Myocytes; Myocardial infarction; Ion channels
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