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Cardiovascular Research 1998 38(2):281-290; doi:10.1016/S0008-6363(98)00044-3
© 1998 by European Society of Cardiology
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Copyright © 1998, European Society of Cardiology

Cardiac endothelium and myocardial function1

Dirk L. Brutsaert*, Paul Fransen, Luc J. Andries, Gilles W. De Keulenaer and Stanislas U. Sys

Department of Physiology and Medicine, University of Antwerp, Antwerp, Belgium

* Corresponding author. Tel.: +32 (3) 218-0277; Fax: +32 (3) 218-0276.

Endocardial endothelium and vascular endothelium of myocardial capillaries share common features as modulators of cardiac performance, rhythmicity and growth. Growing evidence suggests differences between these two cardiac endothelial cell types with regard to developmental, morphological and functional properties. A major difference probably resides in the way and extent by which these endothelial cells perceive and transmit signals.

KEYWORDS Endocardial endothelium; Vascular endothelium; Myocardial capillary; Endothelial factor; Cytokine; Blood–heart barrier; Cardiac performance

1 This Review is a summary of the Basic Science Lecture delivered by Dirk L. Brutsaert at the Annual Scientific Meeting of the ESC, Stockholm (Sweden), August 27, 1997.


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