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Cardiovascular Research 1995 30(2):161-165; doi:10.1016/S0008-6363(95)00030-5
© 1995 by European Society of Cardiology
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Copyright © 1995, European Society of Cardiology

Cardiovascular protection by oestrogen is partly mediated through modulation of autonomic nervous function

Xiao-Jun Du*,a, Rudolph A. Riemersmab and Anthony M. Darta

aBaker Medical Research Institute and Alfred Hospital, Melbourne, Australia
bCardiovascular Research Unit, University of Edinburgh, Edinburgh, UK

* Corresponding author Baker Medical Research Institute, Commercial Road, Prahran, Victoria 3181, Australia, Tel. (03) 522 4396. Fax (03) 5211362.

Experimental studies have provided evidence that the autonomic nervous activity is modulated by oestrogen. Such modulation at central and peripheral levels tends to suppress sympathetic but elevate parasympathetic tone to the cardiovascular system. Thus, available data support the view that cardiovascular protection by oestrogen may, at least in part, be mediated by its influence on autonomic nervous function.

KEYWORDS Estrogen; Sex difference; Autonomic nerves; Myocardial ischemia; Autonomic nervous function


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