Skip Navigation

Cardiovascular Research 1967 1(4):371-378; doi:10.1093/cvr/1.4.371
© 1967 by European Society of Cardiology
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Delin, A.
Right arrow Articles by Teger-Nilsson, A.-C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Delin, A.
Right arrow Articles by Teger-Nilsson, A.-C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Copyright © 1967, European Society of Cardiology

Vasodilatation in the Canine Leg caused by Intra-arterial Infusion of Thrombin and Tissue Thromboplastin*

Anders Delin, Per Olsson and Ann-Catrine Teger-Nilsson

From the Surgical Research Laboratory, Thoracic Clinic, Karolinska Sjukhuset, and the Department of Blood Coagulation Research, Karolinska Institutet, Stockholm, Sweden

Authors' Synopsis: Thrombin was infused into a canine femoral artery. At low concentrations vasodilatation occurred. At high concentrations the vasodilatation was followed by intravascular coagulation. Heparinization of the animal or diisopropylfluorophosphate treatment of the thrombin inhibited both the vasodilating and procoagulant activity. Tissue thromboplastin had similar effects on femoral vascular resistance. Heparinization of the animal inhibited the procoagulant but not the vasodilating activity. In thrombin, but not in tissue thromboplastin, the vasodilating and procoagulant activities are correlated.

* This work was supported by grants from the Swedish National Association against Heart and Chest Diseases and from the Swedish Medical Research Council, 17X-1028-01.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Arch SurgHome page
J. Hoie and W. G. Schenk Jr.
Hemodynamics of Disseminated Intravascular Coagulation: Effects of Intra-Aortic Thrombin Infusions on Renal and Mesenteric Blood Flow in the Dog
Arch Surg, June 1, 1972; 104(6): 838 - 841.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.