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Cardiovascular Research 1967 1(3):210-214; doi:10.1093/cvr/1.3.210
© 1967 by European Society of Cardiology
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Copyright © 1967, European Society of Cardiology

Haem Biosynthesis in the Heart Muscle of Man and the Pig

D. A. L. Watt, Ann C. Lochhead and A. Goldberg

From the University Department of Medicine, Gardiner Institute, Western Infirmary, and Stobhill General Hospital, Glasgow

Authors' Synopsis: Using radioisotopic techniques, haem synthesis has been studied in human and pig cardiac muscle. High levels of haemsynthetase and {delta}-aminolaevulic acid dehydrase have been demonstrated, and newly-formed haem has been traced to myoglobin. The effect of iron upon these enzymes has been studied, and the relevance of these findings to iron storage diseases is discussed.


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