OUP user menu

Basic signalling mechanisms

Reviews

Nitric oxide synthase in post-ischemic remodeling: new pathways and mechanisms
Boris Manoury, Virginie Montiel, Jean-Luc Balligand

Role of microRNAs in the reperfused myocardium towards post-infarct remodelling
Hongyan Zhu, Guo-Chang Fan

The innate immune response in reperfused myocardium
Leo Timmers, Gerard Pasterkamp, Vince C. de Hoog, Fatih Arslan, Yolande Appelman, Dominique P. V. de Kleijn

Autophagy as a therapeutic target for ischaemia /reperfusion injury? Concepts, controversies, and challenges
Karin Przyklenk, Yi Dong, Vishnu V. Undyala, Peter Whittaker

Calcium-mediated cell death during myocardial reperfusion
David Garcia-Dorado, Marisol Ruiz-Meana, Javier Inserte, Antonio Rodriguez-Sinovas, Hans Michael Piper

Role of blood cells in ischaemiareperfusion induced endothelial barrier failure
Stephen F. Rodrigues, D. Neil Granger

The ubiquitin-proteasome system in myocardial ischaemia and preconditioning
Saul R. Powell, Andras Divald

Loss of cardioprotection with ageing
Kerstin Boengler, Rainer Schulz, Gerd Heusch

Cardioprotective growth factors
Derek J. Hausenloy, Derek M. Yellon

Sphingosine kinase regulation and cardioprotection
Joel S. Karliner

Original articles

Loss of the MiR-144/451 Cluster Impairs Ischemic Preconditioning-Mediated Cardioprotection by Targeting Rac-1
Xiaohong Wang, Hongyan Zhu, Xiaowei Zhang, Yong Liu, Jing Chen, Mario Medvedovic, Hongliang Li, Mitchell J. Weiss, Xiaoping Ren, Guo-Chang Fan

Reduction of IL-33 expression exaggerates ischemia/reperfusion-induced myocardial injury in mice with Diabetes Mellitus
Tao Rui, Jinchao Zhang, Xuemei Xu, Yongwei Yao, Raymond Kao, Claudio M. Martin

Ablation of Junctin or Triadin is Associated with Increased Cardiac Injury Following Ischemia-Reperfusion
Wen-Feng Cai, Tracy Pritchard, Stela Florea, Chi-Kueng Lam, Peidong Han, Xiaoyang Zhou, Qunying Yuan, Stephan E. Lehnart, Paul D. Allen, Evangelia G. Kranias

Activation of epidermal growth factor receptor mediates reperfusion arrhythmias in anaesthetized rats
Mei Feng, Ji-Zhou Xiang, Zhang-Yin Ming, Qin Fu, Rong Ma, Qiu-Fang Zhang, Yao-Yan Dun, Lei Yang, Hui Liu

The natural cardioprotective particle HDL modulates connexin43 gap junction channels
Sandrine Morel, Miguel A. Frias, Christian Rosker, Richard W. James, S. Rohr,

Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia
Raymond K. Kudej, Mathew Fasano, Xin Zhao, Gary D. Lopaschuk, Susan K. Fischer, Dorothy E. Vatner, Stephen F. Vatner, E. Douglas Lewandowski

Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia
Zhi-Dong Ge, Irina A. Ionova, Nikolina Vladic, Danijel Pravdic, Naoyuki Hirata, Jeannette Vásquez-Vivar, Phillip F. Pratt, David C. Warltier, Galen M. Pieper, Judy R. Kersten

MG53 participates in ischaemic postconditioning through the RISK signalling pathway
Yan Zhang, Fengxiang Lv, Li Jin, Wei Peng, Ruisheng Song, Jianjie Ma, Chun-Mei Cao, Rui-Ping Xiao

Gαi2-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart
Rachael E. Waterson, Corbin G. Thompson, Nathaniel W. Mabe, Kuljeet Kaur, Jeffery N. Talbot, Richard R. Neubig, Boyd R. Rorabaugh

Group V secretory phospholipase A2 plays a pathogenic role in myocardial ischaemia–reperfusion injury
Toshiaki Yano, Daisuke Fujioka, Yukio Saito, Tsuyoshi Kobayashi, Takamitsu Nakamura, Jun-ei Obata, Kenichi Kawabata, Kazuhiro Watanabe, Yosuke Watanabe, Hideto Mishina, Shun Tamaru, Kiyotaka Kugiyama

Long-term effects of intrauterine growth restriction on cardiac metabolism and susceptibility to ischaemia/reperfusion
Christian F. Rueda-Clausen, Jude S. Morton, Gary D. Lopaschuk, Sandra T. Davidge

GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways
François Vigneron, Pierre Pierre Dos Santos, Sandrine Lemoine, Maryline Bonnet, Liliane Tariosse, Thierry Couffinhal, Cécile Duplaà, Béatrice Jaspard-Vinassa

Lysine deacetylation in ischaemic preconditioning: the role of SIRT1
Sergiy M. Nadtochiy, Emily Redman, Irfan Rahman, Paul S. Brookes

Role of the autonomic nervous system in cardioprotection by remote preconditioning in isoflurane-anaesthetized dogs
John G. Kingma, Denys Simard, Pierre Voisine, Jacques R. Rouleau

Direct evidence of chloride ion efflux in ischaemic and pharmacological preconditioning of cultured cardiomyocytes
Roberto J. Diaz, Alina Hinek, Gregory J. Wilson

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4
Yunhui Cheng, Ping Zhu, Jian Yang, Xiaojun Liu, Shimin Dong, Xiaobin Wang, Bao Chun, Jian Zhuang, Chunxiang Zhang

Gadd45 is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia
Mi-Young Kim, Eun Ji Seo, Dong Ha Lee, Eun Joo Kim, Hye Soo Kim, Hea-Young Cho, Eun Yong Chung, Soo Hwan Lee, Eun Joo Baik, Chang-Hyun Moon, Yi-Sook Jung

Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemiareperfusion injury
Tsuyoshi Kobayashi, Yosuke Watanabe, Yukio Saito, Daisuke Fujioka, Takamitsu Nakamura, Jun-ei Obata, Yoshinobu Kitta, Toshiaki Yano, Kenichi Kawabata, Kazuhiro Watanabe, Hideto Mishina, Sadahiro Ito, Kiyotaka Kugiyama

Transient Ca2 depletion of the sarcoplasmic reticulum at the onset of reperfusion
Carlos A. Valverde, Dmytro Kornyeyev, Marcela Ferreiro, Azad D. Petrosky, Alicia Mattiazzi, Ariel L. Escobar

Ischaemic preconditioning improves proteasomal activity and increases the degradation of PKC during reperfusion
Eric N. Churchill, Julio C. Ferreira, Patricia C. Brum, Luke I. Szweda, Daria Mochly-Rosen

Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion
Volker Rudolph, Tanja K. Rudolph, Francisco J. Schopfer, Gustavo Bonacci, Steven R. Woodcock, Marsha P. Cole, Paul R.S. Baker, Ravi Ramani, Bruce A. Freeman

Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway
Lydia Lacerda, Sarin Somers, Lionel H. Opie, Sandrine Lecour

Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resistant state
Wattamon Srisakuldee, Maya M. Jeyaraman, Barbara E. Nickel, Stphane Tanguy, Zhi-Sheng Jiang, Elissavet Kardami

Development and characterization of a mouse in vitro model of ischaemia-induced ventricular fibrillation
Catherine L. Stables, Michael J. Curtis

Stimulation of cGMP signalling protects coronary endothelium against reperfusion-induced intercellular gap formation
Sascha A. Kasseckert, Claudia Schfer, Angelika Kluger, Dragan Gligorievski, Julia Tillmann, Klaus-Dieter Schlter, Thomas Noll, Heinrich Sauer, Hans Michael Piper, Yaser Abdallah

Role of B-type natriuretic peptide in epoxyeicosatrienoic acid-mediated improved post-ischaemic recovery of heart contractile function
Ketul R. Chaudhary, Sri Nagarjun Batchu, Dipankar Das, Mavanur R. Suresh, John R. Falck, Joan P. Graves, Darryl C. Zeldin, John M. Seubert

High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation
Ronghua Luan, Shaowei Liu, Tao Yin, Wayne Bond Lau, Qiong Wang, Wenyi Guo, Haichang Wang, Ling Tao

Sphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protection
Katherine Sattler, Bodo Levkau

Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice
Gabor Czibik, Julia Sagave, Vladimir Martinov, Bushra Ishaq, Marcus Sohl, Iren Sefland, Harald Carlsen, Filip Farnebo, Rune Blomhoff, Guro Valen

Delayed recovery of intracellular acidosis during reperfusion prevents calpain activation and determines protection in postconditioned myocardium
Javier Inserte, Ignasi Barba, Vctor Hernando, David Garcia-Dorado